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Immunometabolic characteristics of pediatric tumors

Immunometabolic characteristics of pediatric tumors

Many tumors display an altered metabolism compared to healthy tissue, such as an enhanced glucose uptake, aberrant amino acid syntheses or an atypical fatty acid metabolism, facilitating tumor growth and metastatic progress. These alterations can be used as a novel target for innovative therapeutic approaches. Our team investigates therapeutic interventions to interfere with tumor-specific metabolic pathways and the interaction with effector cells of the immune system.

 


Collaborations

Dimitios MougiakakosDepartment of Internal Medicine 5
Alexandra SchambonyDevelopmental Biology